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Laszlo Prokai
  • Male
  • Fort Worth, TX
  • United States
  • Robert A. Welch Chair in…
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Laszlo Prokai's Page

About Laszlo Prokai, Ph.D., D.Sc.

Laszlo Prokai, Ph.D., D.Sc.

(SuperProfessor on Faculty Row)

EXPERT CONSULTANT: Pharmaceutical discovery & preclinical development; Bioanalytics; Mass spectrometry 

Phone: 817-735-2206
Skype: laszlo.prokai
E-mail: Laszlo.Prokai@unthsc.edu

Expertise:

Chemical biology; Medicinal chemistry; Biochemistry; Analytical chemistry; Neurochemistry; Mass spectrometry; Neuropeptides; Proteomics; Posttranslational protein modifications; Metabolomics; Molecular neuropharmacology; Computational biochemistry; CNS drug discovery; Preclinical drug development

Laszlo Prokai, Ph.D., D.Sc.
Robert A. Welch Chair in Biochemistry
Professor of Pharmacology and Neuroscience
University of North Texas Health Science Center at Fort Worth

WORK ADDRESS:

3500 Camp Bowie Boulevard

Fort Worth, TX 76107-2699

Dr. Laszlo Prokai is the first Chair in Biochemistry endowed by The Welch Foundation, one of the United States' oldest and largest private funding sources for basic research, at the UNT Health Science Center. His academic career began as an Assistant Professor at the Department of Pharmaceutics and the Center for Drug Discovery of the College of Pharmacy at the University of Florida. During his tenure there, he rose in rank to Professor in the Department of Medicinal Chemistry, held an Affiliate Professorship at the Department of Chemistry, was a Joint Professor of the Department of Anesthesiology, Scientific Advisor of the Biotechnology Program, and Member of the McKnight Brain Institute. Dr. Prokai has maintained an actively funded research program supported by the National Institutes of Health (NIH) and is recognized nationally and internationally for his work on discovery, medicinal chemistry and chemical biology of central nervous system agents, chemical biology of neuropeptides, proteomics and mass spectrometry. Dr. Prokai also serves as an Adjunct Graduate Faculty at the Texas Christian University, Courtesy Professor at the Department of Anesthesiology, University of Florida, and Adjunct Professor at the Department of Chemistry and Biochemistry, University of Texas at Arlington. In 2002, he was the recipient of a Pro Renovanda Cultura Hungariae Visiting Professorship at the Department of Medical Chemistry, University of Szeged (Hungary). He is a co-founder and Chief Scientific Officer of AgyPharma LLC, a start-up pharmaceutical R&D company brought together to develop his inventions.

Selected Items from Curriculum Vitae:

EDUCATION:

Postdoctoral Training in Medicinal and Bioanalytical Chemistry, 1987–1989, University of Florida, Gainesville

University of Veszprem- (currently University of Pannonia), Hungary-

Ph.D. in Radiochemistry -1983, Summa Cum Laude

M.Sc. in Chemistry - 1980, Summa Cum Laude

B.Sc. in Chemical Engineering - 1978; Summa Cum Laude

CAREER:

Professor and the Robert A. Welch Chair in Biochemistry, Center for Neuroscience Discovery, Institute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, 2015–

Professor and the Robert A. Welch Chair in Biochemistry, Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, 2013–2015

Professor and the Robert A. Welch Chair in Biochemistry, Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, 2010–2013

Robert A. Welch Professor, Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, 2005–2010

Professor, Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, 2002–2005

Professor, Center for Drug Discovery and Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, 2000–2002

Associate Professor, Center for Drug Discovery and Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, 1996–2000

Assistant Professor, Center for Drug Discovery and Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, 1991–1996

Assistant Scientist, Center for Drug Discovery, College of Pharmacy, University of Florida, Gainesville, 1990–1991

Assistant Research Scientist, Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, 1989–1990

Postdoctoral Research Associate, Center for Drug Design and Delivery, Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, 1987–1989

Lecturer and Scientific Advisor (Part-time), University of Veszprem (currently University of Pannonia), Veszprem, Hungary, 1981–1986

Associate Research Scientist, Hungarian Oil and Gas Research Institute, Veszprem, Hungary, 1980-1989, (leave of absence, 1987–1989)

Graduate Research Assistant, Department of Radiochemistry and Physics, University of Veszprem (currently University of Pannonia), Hungary, 1979–1980

AFFILIATIONS:
Scientific Advisor of the Biotechnology Program, University of Florida (2001–2005)

Affiliate Professor, Department of Chemistry, University of Florida (2002–2005)

Courtesy Professor, Department of Medicinal Chemistry, University of Florida (2005–2015)

Joint/Courtesy Professor, Department of Anesthesiology, University of Florida (2005–)

Adjunct Professor, Dept. of Chemistry & Biochemistry, University of Texas at Arlington (2006–)

Adjunct Professor, Dept. of Chemistry, Texas Christian University, Fort Worth, TX (2006–)

Member of the McKnight Brain Institute, University of Florida (1998–2005)

Editorial Advisory Board Member, CNS Agents in Medicinal Chemistry (2000–)

Editorial Advisory Board Member, Current Drug Delivery (2003–)

Editorial Advisory Board Member, Medicinal Chemistry (2004–2014)

Editorial Advisory Board Member, Medicinal Chemistry Reviews Online (2003–2005)

Editorial Advisory Board Member, Current Medicinal Chemistry (2006–)

Editorial Advisory Board Member, Open Medicinal Chemistry Journal (2007–)

Editorial Advisory Board Member, Journal of Data Mining in Genomics & Proteomics (2010–)

Associate Editor, Journal of Integrated Omics (2010–)

Editorial Advisory Board Member, Letters in Drug Design & Discovery (2012–)

Editorial Advisory Board Member, Current Metabolomics (2012–)

Guest Editor, “Fourier Transform Mass Spectrometry in Molecular Sciences,”

International Journal of Molecular Sciences (2014-)

Laszlo Prokai's Publications on ResearchGate.net

Selected Publications:

[Chemical Biology]Access the recommendation on F1000Prime The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders

[Proteomics & Mass Spectrometry] Selective chemoprecipitation to enrich nitropeptides from complex proteomes for mass-spectrometric analysis

[Neuropeptides] Prodrug design for brain delivery of small-and medium-sized neuropeptides

[Medicinal Chemistry] Centrally acting and metabolically stable thyrotropin-releasing hormone analogues by replacement of histidine with substituted pyridinium

[Pharmacology & Therapeutics] Structure–nongenomic neuroprotection relationship of estrogens and estrogen-derived compounds

Profile Information

Job Title
Robert A. Welch Chair in Biochemistry; Professor of Pharmacology and Neuroscience
School
University of North Texas Health Science Center at Fort Worth
Areas of Expertise/Research Interests (List All Please)
Chemical biology; Medicinal chemistry; Biochemistry; Analytical chemistry; Neurochemistry; Mass spectrometry; Neuropeptides; Proteomics; Posttranslational protein modifications; Metabolomics; Molecular neuropharmacology; Computational biochemistry; CNS drug discovery; Preclinical drug development

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At 10:27am on February 17, 2015, Roseane Maria Maia Santos said…

Dear Dr. Prokai:

Thank you for your invitation. We can take advantage of our expertise and maybe have some research collaboration or teaching methods and etc.

Best wishes,

Roseane

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