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Antonio Vidal-puig
  • Male
  • Cambridge
  • United Kingdom
  • Professor of Molecular Nutrition…
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About Antonio Vidal-Puig

CONTACT PROFESSOR Antonio Vidal Puig (Professional Consultant)

University of Cambridge

Voice: 00441223762790

EMAIL: ajv22@cam.ac.uk

EXPERTISE:

Nutrition

Molecular Nutrition and Metabolism

Metabolic Medicine

Metabolic Diseases

Endocrinology

Physiology

Biochemistry

Obesity and Related Disorders

University of Cambridge Metabolic Research Laboratories

Trust-MRC Institute of Metabolic Science

                                   

Current Appointment Professor of Molecular Nutrition and Metabolism Cambridge University/Institute of Metabolic Science

Click Image Below to See Antonio Vidal-Puig's University of Cambridge Links:

Professional History: 

October 2009-

Present            Professor of Molecular Nutrition and Metabolism

                        Honorary Consultant Metabolic Medicine

Deputy Director MRC Metabolic Diseases Unit

Scientific Director Cambridge Phenomics Centre

2006- 2009      Reader in Metabolism and Biochemistry.

                          Honorary Consultant Metabolic Medicine.

Director of the Wellcome Trust Integrative Physiology Mouse Program.

Deputy Director CORD-MRL (Center for Obesity and Related Disorders).

Scientific Director Cambridge Phenomics Centre.

 

2003-2006       Lecturer in Clinical Biochemistry and Metabolic Medicine.

Honorary Consultant Clinical Biochemistry and Metabolic Medicine.

Director of the Wellcome Trust Integrative Physiology Mouse Program.

Professional Qualifications

Executive MBA - Cambridge University

GMC Full registration as a Medical Practitioner- Principal List n: 4660750, 23 Sept 1999.

GMC Specialist Register Endocrinology and Diabetes Mellitus n: 4660750 23 Sep 1999.

Patent

Hart KA, Montague CT, Vidal-Puig A. Human and rat PGC-3, PPAR-gamma coactivations and splice variants thereof. United States Patent- 7306922.

List of Publications (**Selected publications)

 

Click the Image to Buy the Book on Amazon:

Originals

 

  1. Smith MA, Katsouri L, Irvine EE, Hankir MK, Pedroni SM, Voshol PJ, Gordon MW, Choudhury AI, Woods A, Vidal-Puig A, Carling D, Withers DJ.Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice. Cell Rep. 2015 Apr 21;11(3):335-43. doi: 10.1016/j.celrep.2015.03.029. Epub 2015 Apr 9.PMID:25865886

 

  1. Virtue S, Masoodi M, de Weijer BA, van Eijk M, Mok CY, Eiden M, Dale M, Pirraco A, Serlie MJ, Griffin JL, Vidal-Puig A.Prostaglandin profiling reveals a role for haematopoietic prostaglandin D synthase in adipose tissue macrophage polarisation in mice and humans. Int J Obes (Lond). 2015 Mar 24. doi: 10.1038/ijo.2015.34. [Epub ahead of print]

 

  1. Pellegrinelli V, Rouault C, Rodriguez-Cuenca S, Albert V, Edom-Vovard F, Vidal-Puig A, Clément K, Butler-Browne G, Lacasa D. Human adipocytes induce inflammation and atrophy in muscle cells during obesity. Diabetes. 2015 Feb 18. pii: db140796. [Epub ahead of print]

 

  1. Patel MN, Bernard WG, Milev NB, Cawthorn WP, Figg N, Hart D, Prieur X, Virtue S, Hegyi K, Bonnafous S, Bailly-Maitre B, Chu Y, Griffin JL, Mallat Z, Considine RV, Tran A, Gual P, Takeuchi O, Akira S, Vidal-Puig A, Bennett MR, Sethi JK. Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):506-11.

 

  1. Clemente FJ, Cardona A, Inchley CE, Peter BM, Jacobs G, Pagani L, Lawson DJ, Antão T, Vicente M, Mitt M, DeGiorgio M, Faltyskova Z, Xue Y, Ayub Q, Szpak M, Mägi R, Eriksson A, Manica A, Raghavan M, Rasmussen M, Rasmussen S, Willerslev E, Vidal-Puig A, Tyler-Smith C, Villems R, Nielsen R, Metspalu M, Malyarchuk B, Derenko M, Kivisild T. A Selective Sweep on a Deleterious Mutation in CPT1A in Arctic Populations. Am J Hum Genet. 2014 Oct 23;95(5):584-589.

 

  1. Barbarroja N, Rodriguez-Cuenca S, Nygren H, Camargo A, Pirraco A, Relat J, Cuadrado I, Pellegrinelli V, Medina-Gomez G, Lopez-Pedrera C, Tinahones FJ, Symons JD, Summers SA, Oresic M, Vidal-Puig A. Increased dihydroceramide/ceramide ratio mediated by defective expression of degs1 impairs adipocyte differentiation and function. Diabetes. 2014 Oct 28. pii: DB_140359.

 

  1. Charalambous M, Da Rocha ST, Radford EJ, Medina-Gomez G, Curran S, Pinnock SB, Ferrón SR, Vidal-Puig A, Ferguson-Smith AC. DLK1/PREF1 regulates nutrient metabolism and protects from steatosis. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16088-93.

 

  1. Sebastian-Leon P, Vidal E, Minguez P, Conesa A, Tarazona S, Amadoz A, Armero C, Salavert F, Vidal-Puig A, Montaner D, Dopazo J. Understanding disease mechanisms with models of signaling pathway activities. BMC Syst Biol. 2014 Oct 25;8(1):121

 

  1. Ortega FJ, Serrano M, Rodriguez-Cuenca S, Moreno-Navarrete JM, Gómez-Serrano M, Sabater M, Rodriguez-Hermosa JI, Xifra G, Ricart W, Peral B, Vidal-Puig A, Fernández-Real JM. Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPARγ gene expression. J Mol Med (Berl). 2015 Jan;93(1):83-92.

 

  1. Yu, E, Calvert PA, Mercer JR, Harrison J, Baker L, Figg NL, Kumar S, Wang JJ, Hurtst LA, Obaid DR, Logan A, West NE, Clarke MC, Vidal-Puig A, Murphy MP, Bennett MR. Response to letter regarding article, “Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with high-risk plaques in human”. Circulation 2014 Mar 25;129(12):e408. Doi: 10.1161/CIRCULATIONHA. 112.008032.

 

  1. Roberts LD, West JA, Vidal-Puig A, Griffin JL. Methods for performing lipidomics in white adipose tissue. Methods Enzymol. 2014;538:211-31. doi: 10.1016/B978-0-12-800280-3.00012-8. 

 

  1. Vidal-Puig A. Adipose tissue expandability, lipotoxicity and the metabolic syndrome. Endocrinol Nutr. 2013;60 Suppl 1:39-43.

 

  1. Paniagua JA, Escandell-Morales JM, Gil-Contreras D, Berral de la Rosa FJ, Romero-Jimenez M, Gómez-Urbano A, Sanchez-Lopez A, Bellido E, Poyato A, Calatayud B, Vidal-Puig AJ. Central obesity and altered peripheral adipose tissue gene expression characterize the NAFLD patient with insulin resistance: Role of nutrition and insulin challenge. Nutrition. 2014 Feb;30(2):177-85.

 

  1. Sanghez V, Razzoli M, Carobbio S, Campbell M, McCallum J, Cero C, Ceresini G, Cabassi A, Govoni P, Franceschini P, de Santis V, Gurney A, Ninkovic I, Parmigiani S, Palanza P, Vidal-Puig A, Bartolomucci A. Psychosocial stress induces hyperphagia and exacerbates diet-induced insulin resistance and the manifestations of the Metabolic Syndrome. Psychoneuroendocrinology 2013 Sep 2. pii: S0306-4530(13)00287-

 

  1. Moreno-Navarrete JM, Escoté X, Ortega F, Serino M, Campbell M, Michalski MC, Laville M, Xifra G, Luche E, Domingo P, Sabater M, Pardo G, Waget A, Salvador J, Giralt M, Rodriguez-Hermosa JI, Camps M, Kolditz CI, Viguerie N, Galitzky J, Decaunes P, Ricart W, Frühbeck G, Villarroya F, Mingrone G, Langin D, Zorzano A, Vidal H, Vendrell J, Burcelin R, Vidal-Puig A, Fernández-Real JM. A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction. Diabetologia 2013 Nov;56(11):2524-37

 

  1. **Carobbio S, Hagen RM, Lelliott CJ, Slawik M, Medina-Gomez G, Tan CY, Sicard A, Atherton HJ, Barbarroja N, Bjursell M, Bohlooly-Y M, Virtue S, Tuthill A, Lefai E, Laville M, Wu T, Considine RV, Vidal H, Langin D, Oresic M, Tinahones FJ, Fernandez-Real JM, Griffin JL, Sethi JK, López M, Vidal-Puig A. Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity. Diabetes 2013 Aug 6. [Epub ahead of print]

 

  1. Yu E, Calvert PA, Mercer JR, Harrison J, Baker L, Figg NL, Kumar S, Wang JC, Hurst LA, Obaid DR, Logan A, West NE, Clarke MC, Vidal-Puig A, Murphy MP, Bennett MR. Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and correlates with higher-risk plaques in humans. Circulation 2013 Aug 13;128(7):702-12. doi: 10.1161/CIRCULATIONAHA.113.002271. Epub 2013 Jul 10

 

  1. Camacho A, Huang JK, Delint-Ramirez I, Yew Tan C, Fuller M, Lelliott CJ, Vidal-Puig A, Franklin RJ. Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis. Eur J Neurosci 2013 Jun 14. doi: 10.1111/ejn.12281. [Epub ahead of print].

 

  1. Alligier M, Gabert L, Meugnier E, Lambert-Porcheron S, Chanseaume E, Pilleul F, Debard C, Sauvinet V, Morio B, Vidal-Puig A, Vidal H, Laville M. Visceral fat accumulation during lipid overfeeding is related to subcutaneous adipose tissue characteristics in healthy men. J Clin Endocrinol Metab 2013 Feb;98(2):802-10 (2013)

 

  1. Virtue S, Even P, Vidal-Puig A. Below Thermoneutrality, Changes in Activity Do Not Drive Changes in Total Daily Energy Expenditure between Groups of Mice. Cell Metab Nov 7;16(5):665-71 (2012)

 

  1. Mercader JM, Puiggros M, Segrè AV, Planet E, Sorianello E, Sebastian D, Rodriguez-Cuenca S, Ribas V, Bonàs-Guarch S, Draghici S, Yang C, Mora S, Vidal-Puig A, Dupuis J; DIAGRAM Consortium, Florez JC; MITIN Consortium, Zorzano A, Torrents D. Identification of Novel Type 2 Diabetes Candidate Genes Involved in the Crosstalk between the Mitochondrial and the Insulin Signaling Systems. PLoS Genet 2012 Dec;8(12):e1003046.

 

  1. Virtue S, Feldmann H, Christian M, Tan CY, Masoodi M, Dale M, Lelliott C,  Burling K, Campbell M, Eguchi N,  Voshol P, Sethi JK, Parker M, Urade Y, Griffin JL, Cannon B, Vidal-Puig A. A new role for Lipocalin Prostaglandin D Synthase in the regulation of brown adipose tissue substrate utilisation. Diabetes 61(12):3139-47 (2012).

 

  1. Bartolomucci A, Parmigiani S, Rodgers RJ, Vidal-Puig A, Allan SE, Siegel V. The Obese Species: a special issue on obesity and metabolic disorders. Dis Model Mech 2012 Sep;5(5):563-4

 

  1. Virtue S, Masoodi M, Velagapudi V, Tan CY, Dale M, Suorti T, Slawik M, Blount M, Burling K, Campbell M, Eguchi N, Medina-Gomez G, Sethi JK, Orešič M, Urade Y, Griffin JL, Vidal-Puig A. Lipocalin Prostaglandin D Synthase and PPARγ2 Coordinate to Regulate Carbohydrate and Lipid Metabolism In Vivo. PLoS One 7(7):e39512. (2012)

 

  1. Camacho A, Rodriguez-Cuenca C, Blount M, Prieur X, Barbarroja N, Fuller M, Hardingham GE, Antonio Vidal-Puig. Ablation of PGC1 beta prevents mTOR dependent endoplasmic Reticulum Stress response. Experimental Neurology 237(2):396-406 (2012)

Associate Faculty Wellcome Trust Sanger Institute 

EAS Advanced Course in Cardiometabolic Phenotyping in Rodents

General information (Link)

Course date

The 3-day course will take place Tuesday 30 June - Thursday 2nd July, 2015.

Course location

The Course will be held at the University of Cambridge.

Directors of the Course
  • Antonio Vidal-Puig, Institute of Metabolic Science, University of Cambridge
  • Sam Virtue, Institute of Metabolic Science, University of Cambridge
  • Barry Rosen, Wellcome Trust Sanger Institute
  • Thomas Krieg, University of Cambridge
  • Ziad Mallat, University of Cambridge

 

Profile Information

Job Title
Professor of Molecular Nutrition and Metabolism
School
University of Cambridge
Areas of Expertise/Research Interests (List All Please)
Toni Vidal-Puig is currently the Professor of Molecular Nutrition and Metabolism at Cambridge University and Honorary Consultant in Metabolic Medicine at Addenbrooke’s Hospital, Cambridge.

Follow the TVPLab on Twitter
https://twitter.com/tvplab

He is Principal investigator at the MRC MDU Unit and Director of the Cambridge Phenomics Center, a state-of-the-art center that applies multidisciplinary approaches to murine phenotyping.

His programme of research focuses on the molecular mechanisms of lipid-induced insulin resistance and on developing strategies to prevent the deleterious effects of lipids, specifically by modulating fatty acid oxidation and thermogenic mechanisms.

He is interested in strategy and innovation in academic research intensive institutions and in identifying the best practices to manage talent. Currently is develop these interests studying for an EMBA at the Judge Institute of the University of Cambrige due in May 2015.

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